Passive antibody to Bartonella henselae protects against clinical disease following homologous challenge but does not prevent bacteremia in cats.
نویسندگان
چکیده
We challenged cats transfused with anti-Bartonella serum and kittens born to antibody-positive queens with Bartonella henselae to determine the contribution of antibodies to the control of B. henselae in cats. In both experiments, antibody-positive cats were protected from clinical disease but passive antibody to the homologous strain of B. henselae did not prevent bacteremia.
منابع مشابه
Bartonella henselae infection in cats: evaluation during primary infection, treatment, and rechallenge infection.
Bartonella henselae infection was established in eight cats of various ages by experimental inoculation. All cats remained persistently bacteremic until they were treated 4 to 7 weeks after primary inoculation. Antibody titers increased and peaked between 4 and 12 weeks for all cats. Treatment with doxycycline for 1 week was effective in suppressing bacteremia in all cats but was effective in c...
متن کاملBartonella henselae prevalence in domestic cats in California: risk factors and association between bacteremia and antibody titers.
The isolation of Bartonella henselae, the agent of cat scratch disease, from the blood of naturally infected domestic cats and the demonstration that cats remain bacteremic for several months suggest that cats play a major role as a reservoir for this bacterium. A convenience sample of 205 cats from northern California was selected between 1992 and 1994 to evaluate the B. henselae antibody and ...
متن کاملInfection and re-infection of domestic cats with various Bartonella species or types: B. henselae type I is protective against heterologous challenge with B. henselae type II.
Four Bartonella species have been isolated from domestic cats, of which two serotypes/genotypes of Bartonella henselae and possibly B. clarridgeiae are human pathogens, causing cat scratch disease (CSD).Our objectives were to evaluate infection and potential cross-protection during re-infection in domestic cats with various Bartonella species or types.Thirty-six cats were primarily inoculated w...
متن کاملAcute clinical disease in cats following infection with a pathogenic strain of Bartonella henselae (LSU16).
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متن کاملPassive immunization does not provide protection against experimental infection with Mycoplasma haemofelis
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ورودعنوان ژورنال:
- Infection and immunity
دوره 69 3 شماره
صفحات -
تاریخ انتشار 2001